Description

Benzene, 5-Bromo-1,2-Dichloro-3-(Trifluoromethyl)- is a highly functionalized halogenated benzene derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique combination of bromo, chloro, and trifluoromethyl substituents on the aromatic ring makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly those requiring halogenated or fluorinated aromatic cores for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common pharmacophore.
• Material Science Research: Serves as a precursor for specialty monomers and ligands used in the development of advanced polymers, liquid crystals, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromo substituent is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira), enabling rapid diversification of the aromatic scaffold.
• Fluorine Chemistry Building Block: The presence of the CF3 group makes it a valuable starting material for introducing fluorine atoms into target molecules, a common strategy in modern medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and the discovery of new synthetic transformations involving polyhalogenated arenes.

Basic Information

Product Name	Benzene, 5-Bromo-1,2-Dichloro-3-(Trifluoromethyl)-
CAS No.	392-89-2
Molecular Formula	C7H2BrCl2F3
Molecular Weight	293.90 g/mol
Synonyms	5-Bromo-1,2-dichloro-3-(trifluoromethyl)benzene; 1-Bromo-2,3-dichloro-5-(trifluoromethyl)benzene; 2,3-Dichloro-5-bromobenzotrifluoride; 3-Bromo-4,5-dichlorobenzotrifluoride; Benzene, 1-bromo-2,3-dichloro-5-(trifluoromethyl)-; 5-Bromo-2,3-dichloro-alpha,alpha,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our Benzene, 5-Bromo-1,2-Dichloro-3-(Trifluoromethyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing the specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.