Description

2,4-Difluoro-1,3,5-Trimethylbenzene is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a sterically defined and electron-deficient scaffold for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates where the difluoro and trimethyl groups modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where its fluorinated aromatic core contributes to the efficacy and environmental profile of the final product.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its structure influences electronic properties and mesomorphic behavior.
• Polymer & Resin Modifier: Employed to introduce fluorine atoms into polymer backbones or side chains, enhancing properties such as chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to the activated fluorine atoms.
• Chemical Research & Development: A valuable standard and starting material in academic and industrial R&D for exploring new fluorination methodologies and creating novel chemical entities.

Basic Information

Product Name	2,4-Difluoro-1,3,5-Trimethylbenzene
CAS No.	392-61-0
Molecular Formula	C9H10F2
Molecular Weight	156.17 g/mol
Synonyms	1,3,5-Trimethyl-2,4-difluorobenzene; 2,4-Difluoro-mesitylene; Mesitylene, 2,4-difluoro-; 2,4-Difluoro-1,3,5-trimethyl-benzene; Benzene, 2,4-difluoro-1,3,5-trimethyl-; Difluoromesitylene
EINECS	206-881-0

Quality Control

Our 2,4-Difluoro-1,3,5-Trimethylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.