Description

2-(Trifluoromethyl)Cyclohexane-1-Carboxylic Acid is a versatile fluorinated organic building block characterized by its cyclohexane backbone and trifluoromethyl group. This combination is critical for modifying the lipophilicity, metabolic stability, and binding affinity of target molecules in advanced synthesis. It is primarily sought after by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the CF₃ group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a fluorinated component in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes.
• Advanced Polymer Modifiers: Incorporated to create specialty polymers with improved chemical resistance and unique surface properties.
• Catalyst & Ligand Development: Employed in the design of novel chiral catalysts and ligands for asymmetric synthesis.
• Chemical Research & Development: A valuable reagent for exploring new fluorination chemistry and structure-activity relationships (SAR) in academic and industrial labs.

Basic Information

Product Name	2-(Trifluoromethyl)Cyclohexane-1-Carboxylic Acid
CAS No.	384-20-3
Molecular Formula	C₈H₁₁F₃O₂
Molecular Weight	196.17 g/mol
Synonyms	2-(Trifluoromethyl)cyclohexanecarboxylic acid; α-(Trifluoromethyl)cyclohexaneacetic acid; Hexahydro-α-(trifluoromethyl)benzenecetic acid; 2-Trifluoromethylcyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 2-(trifluoromethyl)-; 1-Cyclohexanecarboxylic acid, 2-(trifluoromethyl)-; 384-20-3; NSC 406079
EINECS	206-846-3

Quality Control

Our production of 2-(Trifluoromethyl)Cyclohexane-1-Carboxylic Acid adheres to stringent in-process controls and final batch testing to ensure consistent purity and performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.