Description

2-(Bromomethyl)-1,1,1,3,3,3-Hexafluoropropane is a specialized fluorinated bromoalkane building block, valued for its unique combination of a reactive bromomethyl group and a highly fluorinated, lipophilic propyl backbone. This structure makes it a critical intermediate for introducing fluorinated segments into target molecules, enhancing properties like chemical stability, lipophilicity, and metabolic resistance. It is primarily sought by R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel compounds and functional polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs to improve bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a key building block for creating novel fluorinated pesticides and herbicides with enhanced efficacy and environmental persistence.
• Polymer & Material Science: Employed as a monomer or cross-linking agent in the production of specialty fluoropolymers with unique surface properties, chemical resistance, and low dielectric constants.
• Liquid Crystal & Electronic Chemicals: Acts as a precursor for fluorinated components in liquid crystal mixtures and electronic coating materials.
• Organic Synthesis Reagent: Utilized as an alkylating agent or a source of the -CH2CF(CF3)2 moiety in complex organic synthesis for pharmaceuticals and fine chemicals.
• Surface Modification: Used to create fluorinated surfaces on various substrates to impart oil- and water-repellent characteristics.

Basic Information

Product Name	2-(Bromomethyl)-1,1,1,3,3,3-Hexafluoropropane
CAS No.	382-14-9
Molecular Formula	C4H3BrF6
Molecular Weight	244.96 g/mol
Synonyms	1-Bromo-2-(trifluoromethyl)-3,3,3-trifluoropropane; 3-Bromo-1,1,1,3,3,3-Hexafluoro-2-(fluoromethyl)propane (common misnomer); 2-Bromomethylhexafluoropropane; Hexafluoro-2-(bromomethyl)propane; 1,1,1,3,3,3-Hexafluoro-2-(bromomethyl)propane; Perfluoro-tert-butyl bromide analog; (Bromomethyl)perfluoroisopropane
EINECS	206-848-1

Quality Control

Our 2-(Bromomethyl)-1,1,1,3,3,3-Hexafluoropropane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.8 g/mL
Refractive Index (n20/D)	~1.31

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.