Description

3-Bromo-1,1,1-Trifluoro-2-Propanol is a versatile fluorinated organic building block characterized by its reactive bromine and trifluoromethyl groups. This compound matters for its role as a key intermediate in the synthesis of advanced pharmaceuticals, agrochemicals, and specialty materials, where the introduction of fluorine atoms is critical for modulating biological activity and physical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering surface properties, chemical resistance, and weatherability.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution and coupling reactions to incorporate the 1,1,1-trifluoro-2-hydroxypropyl moiety into target molecules.
• Research & Development: A valuable reagent in academic and industrial laboratories for exploring new fluorination methodologies and creating compound libraries.

Basic Information

Product Name	3-Bromo-1,1,1-Trifluoro-2-Propanol
CAS No.	431-34-5
Molecular Formula	C3H4BrF3O
Molecular Weight	192.96 g/mol
Synonyms	2-Propanol, 3-bromo-1,1,1-trifluoro-; 3-Bromo-1,1,1-trifluoropropan-2-ol; 1,1,1-Trifluoro-3-bromo-2-propanol; 3-Bromo-1,1,1-trifluoro-2-hydroxypropane; 3-Bromo-1,1,1-trifluoroisopropyl alcohol; 2-Hydroxy-3-bromo-1,1,1-trifluoropropane; TFBP; BTFP
EINECS	207-082-5

Quality Control

Our 3-Bromo-1,1,1-Trifluoro-2-Propanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all commercial quantities, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.