Description

1-Iodo-3,3,3-Trifluoropropane is a versatile fluorinated organic building block, valued for its unique combination of a reactive iodoalkyl group and a stable trifluoromethyl moiety. This compound is essential for introducing the trifluoropropyl group into target molecules, a modification that can dramatically alter physical and biological properties. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in synthesis, catalysis, and material science.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating compounds with enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel herbicides, insecticides, and fungicides with improved efficacy.
• Liquid Crystal & OLED Material Production: Employed in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes.
• Catalysis & Ligand Development: Acts as a reagent or precursor in catalytic cycles and for synthesizing specialized ligands in transition metal chemistry.
• Polymer Modification: Used to incorporate fluorine into polymer backbones or side chains, imparting properties like chemical resistance and low surface energy.
• Radiolabeling Precursor: Can be utilized as a starting material for the synthesis of iodine-123 or iodine-131 labeled compounds for medical imaging and therapy.

Basic Information

Product Name	1-Iodo-3,3,3-Trifluoropropane
CAS No.	460-37-7
Molecular Formula	C3H4F3I
Molecular Weight	223.96 g/mol
Synonyms	3,3,3-Trifluoro-1-iodopropane; 3-Iodo-1,1,1-trifluoropropane; 1,1,1-Trifluoro-3-iodopropane; Trifluoropropyl iodide; ω-Iodoperfluoropropane; 3,3,3-Trifluoropropyl iodide; Iodotrifluoropropane; TFPI
EINECS	207-317-6

Quality Control

Our 1-Iodo-3,3,3-Trifluoropropane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat and ignition sources. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.95 g/mL
Boiling Point	~105-107°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.