Description

1,1,1-Trifluoro-2-Iodo-Propane is a versatile fluorinated and iodinated organic building block. This compound is valued for its unique reactivity profile, enabling the introduction of both trifluoromethyl and iodine functional groups into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for advanced synthesis and molecular modification.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorine motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a starting material for synthesizing specialized fluorinated polymers, liquid crystals, and electronic chemicals.
• Cross-Coupling Reactions: Acts as an electrophilic reagent in palladium-catalyzed cross-coupling reactions (e.g., Negishi, Suzuki) for carbon-carbon bond formation.
• Radical Chemistry: Utilized as a source of iodopropyl radicals in radical addition and cyclization reactions for constructing complex organic frameworks.
• Fluorine Chemistry Research: An essential reagent in academic and industrial laboratories exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	1,1,1-Trifluoro-2-Iodo-Propane
CAS No.	118334-95-5
Molecular Formula	C3H4F3I
Molecular Weight	223.96 g/mol
Synonyms	2-Iodo-1,1,1-trifluoropropane; 1,1,1-Trifluoro-2-iodopropane; 2-Iodopropyl trifluoride; 3,3,3-Trifluoro-2-iodopropane; Trifluoromethyl(iodo)ethane; Propane, 1,1,1-trifluoro-2-iodo-; TFIP
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-2-Iodo-Propane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.9 g/mL
Boiling Point	~105-110°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.