Description

1-Propanone, 1-Cyclohexyl-2-Fluoro-2-Methyl- (9Ci) is a specialized fluorinated ketone building block, identified by CAS number 130485-81-3. This compound is valued for its unique molecular structure, which incorporates both a cyclohexyl group and a fluorine atom adjacent to the carbonyl, making it a versatile intermediate for introducing steric bulk and fluorine-based electronic effects. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly where fluorine substitution is desired to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom to enhance biological activity and environmental persistence.
• Advanced Material Research: Acts as a precursor in the development of specialty polymers, liquid crystals, and organic electronic materials where the specific steric and electronic properties are critical.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecular architectures, including natural product analogs and novel heterocycles.
• Fluorine Chemistry Studies: Utilized as a model compound in methodological development for fluorination reactions and studying fluorine's impact on reaction pathways.

Basic Information

Product Name	1-Propanone, 1-Cyclohexyl-2-Fluoro-2-Methyl- (9Ci)
CAS No.	130485-81-3
Molecular Formula	C10H17FO
Molecular Weight	172.24 g/mol
Synonyms	1-Cyclohexyl-2-fluoro-2-methylpropan-1-one; 2-Fluoro-2-methyl-1-cyclohexyl-1-propanone; α-Fluoro-α-methylcyclohexyl methyl ketone; 1-Cyclohexyl-2-fluoro-2-methylpropanone; 130485-81-3 (CAS); Fluorinated cyclohexyl propanone; Cyclohexyl fluoromethyl ketone derivative
EINECS	Contact for details

Quality Control

Our production of 1-Propanone, 1-Cyclohexyl-2-Fluoro-2-Methyl- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and synthesis applications. All materials are supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to verify specifications. Custom synthesis and purification to meet specific R&D grade requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is between 2°C and 8°C for long-term stability. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.