Description

2-Fluoro-1-Iodo-2-Methylpropane is a versatile halogenated organic building block, specifically a fluorinated and iodinated alkane. This compound is valued for its dual reactive sites, making it a crucial intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of novel fluorinated pesticides and herbicides, leveraging the fluorine atom's metabolic stability.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals where fluorine substitution modifies physical properties.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi).
• Nucleophilic Substitution: The primary iodide is highly reactive towards nucleophiles, enabling the introduction of various functional groups.
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) in medicinal chemistry due to the fluorine atom.

Basic Information

Product Name	2-Fluoro-1-Iodo-2-Methylpropane
CAS No.	19869-79-5
Molecular Formula	C4H8FI
Molecular Weight	202.01 g/mol
Synonyms	1-Iodo-2-fluoro-2-methylpropane; 2-Fluoro-2-methyl-1-iodopropane; (2-Fluoro-2-methylpropyl)iodide; 2-Methyl-2-fluoropropyl iodide; Isobutyl iodide, 2-fluoro-; 19869-79-5; tert-Butyl fluoro iodide (common name)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-1-Iodo-2-Methylpropane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its light-sensitive and highly volatile nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for optimal long-term stability. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.