Description

2-Fluoropyridine is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring a fluorine atom adjacent to the nitrogen in the pyridine ring, makes it a critical intermediate for introducing fluoropyridine motifs into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluoropyridine moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of fluorinated liquid crystals, organic semiconductors, and other functional materials.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological systems and enzyme mechanisms.
• Custom Synthesis and Scale-up: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) performing custom fluorination chemistry.

Basic Information

Product Name	2-Fluoropyridine
CAS No.	372-48-5
Molecular Formula	C5H4FN
Molecular Weight	97.09 g/mol
Synonyms	2-Fluoropyridine; α-Fluoropyridine; 2-Fluoro-pyridine; Pyridine, 2-fluoro-; 2-FP; NSC 71968; FPy; 2-Fluoropyridin
EINECS	206-753-6

Quality Control

Every batch of 2-Fluoropyridine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.