Description

4-Pyridinecarboxamide,2-Fluoro- CAS NO 369-01-7 is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for introducing the 2-fluoro-pyridine moiety into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluoropyridine structure enhances biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic and binding studies.
• Custom Synthesis and Scale-up: A critical building block for contract research and manufacturing organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	4-Pyridinecarboxamide,2-Fluoro-
CAS No.	369-01-7
Molecular Formula	C6H5FN2O
Molecular Weight	140.12 g/mol
Synonyms	2-Fluoropyridine-4-carboxamide; 2-Fluoroisonicotinamide; 2-Fluoro-4-pyridinecarboxamide; 2-Fluoro-4-carbamoylpyridine; 4-Carbamoyl-2-fluoropyridine; 2-Fluoropyridine-4-carboxylic acid amide; 2-Fluoroisonicotinic acid amide; 369-01-7
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoroisonicotinamide is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if opened for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.