Description

3-Aminobenzenesulfonyl Fluoride is a key aromatic sulfonyl fluoride derivative, serving as a versatile and reactive building block in advanced organic synthesis. Its primary value lies in its role as a selective and efficient sulfonylation reagent, particularly in the development of pharmaceutical intermediates and bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the sulfonamide pharmacophore or create sulfonyl-based linkers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drugs, including protease inhibitors, kinase inhibitors, and antibacterial agents.
• Chemical Biology & Proteomics: Used as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors due to the electrophilic sulfur-fluorine bond.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that contain the sulfonamide functional group.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Dye & Pigment Manufacturing: Serves as an intermediate in the synthesis of sulfonated dyes and colorants.
• Research & Development: A valuable tool for medicinal chemists and organic chemists exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	3-Aminobenzenesulfonyl Fluoride
CAS No.	368-50-3
Molecular Formula	C6H6FNO2S
Molecular Weight	175.18 g/mol
Synonyms	m-Aminobenzenesulfonyl Fluoride; 3-Aminophenylsulfonyl Fluoride; Benzenesulfonyl fluoride, 3-amino-; Meta-Aminobenzenesulfonyl Fluoride; 3-Amino-1-fluorosulfonylbenzene; 3-Aminophenyl Sulfonyl Fluoride; 3-Aminosulfonylfluorobenzene; 3-Fluorosulfonylaniline
EINECS	206-707-2

Quality Control

Our 3-Aminobenzenesulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.