Description

2-Acetamido-4-Fluorotoluene is a specialized fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both an acetamido and a fluorine substituent on a toluene backbone, enabling precise modifications in target molecules. This intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in electronic display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the research and production of specialized electron-transport or host materials.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new fluorination reactions and heterocyclic chemistry.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes with unique color fastness and spectral properties.

Basic Information

Product Name	2-Acetamido-4-Fluorotoluene
CAS No.	366-49-4
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	N-(4-Fluoro-2-methylphenyl)acetamide; 4'-Fluoro-2'-methylacetanilide; 2-Methyl-4-fluoroacetanilide; 4-Fluoro-2-methylacetanilide; 2-Acetamido-4-fluorotoluene; 2-Acetylamino-4-fluorotoluene; N-Acetyl-4-fluoro-o-toluidine; Acetamide, N-(4-fluoro-2-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2-Acetamido-4-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.