Description

3-Fluoropyridine-4-Carbohydrazide is a versatile fluorinated pyridine derivative, a key heterocyclic building block prized for its reactive carbohydrazide functional group. This compound is essential for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is a critical raw material for researchers and manufacturers in pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated pyridine motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Chelating Agent Precursor: The carbohydrazide group serves as a versatile handle for constructing complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and creating libraries of compounds for high-throughput screening.
• Material Science: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and advanced materials with tailored properties.

Basic Information

Product Name	3-Fluoropyridine-4-Carbohydrazide
CAS No.	364-82-9
Molecular Formula	C6H6FN3O
Molecular Weight	155.13 g/mol
Synonyms	4-Hydrazinecarbonyl-3-fluoropyridine; 3-Fluoroisonicotinic acid hydrazide; 3-Fluoro-4-pyridinecarbohydrazide; 3-Fluoropyridine-4-carboxylic acid hydrazide; 3-Fluoroisonicotinohydrazide; Isonicotinic acid, 3-fluoro-, hydrazide; 3-Fluoro-4-pyridylcarbohydrazide
EINECS	Contact for details

Quality Control

Our 3-Fluoropyridine-4-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.