Description

2-Fluoronicotinamide is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and an amide group on the pyridine ring, makes it an invaluable intermediate for creating novel compounds with targeted biological activity. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorinated motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the creation of novel fluorinated polymers, liquid crystals, and electronic materials for specialized applications.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and other molecular probes used in diagnostic and biochemical research.

Basic Information

Product Name	2-Fluoronicotinamide
CAS No.	364-22-7
Molecular Formula	C6H5FN2O
Molecular Weight	140.12 g/mol
Synonyms	2-Fluoropyridine-3-carboxamide; 3-Carbamoyl-2-fluoropyridine; Nicotinamide, 2-fluoro-; 2-Fluoro-3-pyridinecarboxamide; 2-Fluoronicotinic acid amide; 2-Fluoronicotinamide (common name); 2-Fluoropyridine-3-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 2-Fluoronicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.