Description

Prostaglandin E2 (PGE2) is a vital endogenous lipid mediator, or eicosanoid, that plays a central role in numerous physiological and pathological processes. Its primary value lies in its potent biological activity, influencing processes such as inflammation, smooth muscle contraction, and cellular proliferation. This makes it an essential compound for research and development within the pharmaceutical, biotechnology, and life science sectors, particularly for studying inflammatory pathways, reproductive biology, and cancer research. CAS No. 363-24-6.

Application

• Pharmaceutical Research & Development: A key reference standard and active agent in drug discovery programs targeting inflammation, pain, and fever.
• Cell Culture & Biomedical Research: Used to study cellular signaling pathways, immune response modulation, and tissue regeneration in vitro.
• Reproductive Health Studies: Critical for investigating uterine contractility, cervical ripening, and other processes in obstetrics and gynecology research.
• Inflammation and Immunology: Serves as a fundamental tool for modeling inflammatory diseases and understanding the role of eicosanoids in the immune system.
• Oncology Research: Employed to examine the role of prostaglandins in tumor progression, angiogenesis, and metastasis.
• Biochemical Synthesis: Acts as a key intermediate or precursor in the synthesis of more complex prostaglandin analogs and derivatives.

Basic Information

Product Name	Prostaglandin E2
CAS No.	363-24-6
Molecular Formula	C20H32O5
Molecular Weight	352.47 g/mol
Synonyms	PGE2; Dinoprostone; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; Prostaglandin E2; U-12062; Prostin E2
EINECS	206-656-4

Quality Control

Our Prostaglandin E2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	-55° to -65° (c=1 in THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.