Description

13,14-Dihydro-15-Keto Prostaglandin E2 is a key metabolite and synthetic intermediate in the study of prostaglandin pathways and their biological activities. This compound is of significant value for pharmaceutical research and development, particularly in the investigation of inflammation, pain, and reproductive physiology. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery, analytical method development, and biochemical studies.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and synthetic intermediate for developing novel therapeutics targeting prostaglandin receptors.
• Biochemical Assays: Used as a substrate or inhibitor in enzymatic studies to elucidate the metabolism and function of prostaglandins.
• Analytical Chemistry: Employed as a high-purity certified reference material (CRM) for the calibration of HPLC, LC-MS, and GC-MS systems in bioanalytical laboratories.
• Metabolic Pathway Studies: Essential for investigating the catabolic pathways of Prostaglandin E2 (PGE2) and understanding related physiological and pathological processes.
• Academic Research: Utilized in university and institutional labs for fundamental research in pharmacology, endocrinology, and cell signaling.

Basic Information

Product Name	13,14-Dihydro-15-Keto Prostaglandin E2
CAS No.	363-23-5
Molecular Formula	C20H32O5
Molecular Weight	352.47 g/mol
Synonyms	15-Keto-13,14-dihydro-PGE2; 15-Keto-DH-PGE2; 11α,15-Dihydroxy-9-oxoprost-13-en-1-oic acid; 13,14-Dihydro-15-keto-PGE2; 13,14-Dihydro-15-oxo-prostaglandin E2; PGE2 metabolite; 15-Keto-13,14-dihydroprostaglandin E2
EINECS	Contact for details

Quality Control

Our 13,14-Dihydro-15-Keto Prostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.