Description

13,14-Dihydroprostaglandin E2 is a key synthetic prostaglandin analog and a stable metabolite of Prostaglandin E2 (PGE2). This compound is of significant value in biochemical and pharmacological research due to its role in studying the PGE2 pathway with reduced susceptibility to enzymatic degradation. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences industries for drug discovery, target validation, and as a reference standard in analytical applications.

Application

• Biochemical Research: Used as a stable analog to investigate the biological functions and signaling pathways of Prostaglandin E2.
• Pharmaceutical R&D: Serves as a critical intermediate or reference compound in the development of novel therapeutics targeting inflammation, pain, and reproductive health.
• Analytical Standard: Employed as a high-purity reference standard in HPLC, LC-MS, and other analytical methods for quality control and quantification.
• Cell Biology Studies: Applied in *in vitro* assays to study cellular responses, receptor binding, and enzyme activity related to the eicosanoid pathway.
• Metabolic Pathway Analysis: A vital tool for probing the metabolism and downstream effects of prostaglandins in various biological systems.

Basic Information

Product Name	13,14-Dihydroprostaglandin E2
CAS No.	363-22-4
Molecular Formula	C₂₀H₃₄O₅
Molecular Weight	354.48 g/mol
Synonyms	13,14-Dihydro-PGE2; DH-PGE2; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 13,14-Dihydroprostaglandin E2; PGE2 metabolite; 13,14-DH-PGE2; 9-Oxo-11,15-dihydroxyprosta-5,13-dien-1-oic Acid
EINECS	Contact for details

Quality Control

Our 13,14-Dihydroprostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. This product is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.