Description

Trifluoroacetyl Bromide is a highly reactive acyl bromide derivative, distinguished by the presence of three fluorine atoms on the acetyl group. This compound is a critical fluorinated building block valued for its ability to introduce the trifluoroacetyl moiety into target molecules, significantly altering their physicochemical properties. It is essential for manufacturers and researchers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediates: Key reagent for synthesizing trifluoroacetyl-protected amines and amino acids, a common step in peptide and active pharmaceutical ingredient (API) manufacturing.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds that improve the performance and durability of electronic display materials.
• Polymer Modification: Employed to introduce fluorine into polymer chains, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis & Research: A versatile reagent for acylations and as a starting material for various trifluoromethyl-containing heterocycles and complex molecules in R&D laboratories.

Basic Information

Product Name	Trifluoroacetyl Bromide
CAS No.	354-31-4
Molecular Formula	C2BrF3O
Molecular Weight	176.93 g/mol
Synonyms	Trifluoroacetic acid bromide; Bromotrifluoroacetone; Perfluoroacetyl bromide; 2,2,2-Trifluoroacetyl bromide; TFAB; CF3C(O)Br; Trifluoroethanoyl bromide
EINECS	206-557-6

Quality Control

Our Trifluoroacetyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.