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3-Fluorotoluene CAS NO 352-70-5


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CAS No.:352-70-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Fluorotoluene is a versatile fluorinated aromatic building block, essential for introducing the fluoromethylphenyl moiety into complex molecular structures. Its primary value lies in its role as a key intermediate in the synthesis of advanced pharmaceuticals, agrochemicals, and specialty materials, where the fluorine atom enhances metabolic stability and bioavailability. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and liquid crystal industries for constructing active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A crucial synthon for the manufacture of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom improves lipophilicity and biological activity.
  • Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
  • Organic Synthesis & Research: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a precursor for other fluorinated aromatics in academic and industrial R&D laboratories.
  • Specialty Polymer Modifier: Can be incorporated into polymer chains to alter physical properties such as chemical resistance and thermal stability.
  • Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name 3-Fluorotoluene
CAS No. 352-70-5
Molecular Formula C7H7F
Molecular Weight 110.13 g/mol
Synonyms m-Fluorotoluene; 1-Fluoro-3-methylbenzene; 3-Methylfluorobenzene; m-Tolyl fluoride; 3-Methyl-1-fluorobenzene; (3-Fluorophenyl)methane; meta-Fluorotoluene
EINECS 206-519-9

Quality Control

Our 3-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent evaporation and moisture absorption.

Specification

Item Specification
Appearance Clear, colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 98.0%
Water Content (KF) ≤ 0.1%
Related Substances (GC) Total impurities ≤ 2.0%
Density (20°C) 1.000 - 1.005 g/mL
Refractive Index (n20D) 1.468 - 1.472

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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