Description

p-Fluorotoluene is a versatile fluorinated aromatic building block essential for advanced organic synthesis. Its value lies in the unique reactivity of the fluorine atom, enabling precise chemical modifications that are difficult to achieve with other substituents. This compound is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and liquid crystal industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: A key starting material for synthesizing fluorinated drug candidates, leveraging the fluorine atom to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine moiety enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a core component in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution to introduce the p-fluorotolyl group into complex molecules.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers with tailored thermal and chemical resistance properties.
• Research & Development: A standard reagent in academic and industrial labs for exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	p-Fluorotoluene
CAS No.	352-32-9
Molecular Formula	C7H7F
Molecular Weight	110.13 g/mol
Synonyms	4-Fluorotoluene; 1-Fluoro-4-methylbenzene; p-Methylfluorobenzene; 4-Methylfluorobenzene; para-Fluorotoluene; F-Toluene; 4-Fluoro-1-methylbenzene; p-Tolyl fluoride
EINECS	206-519-5

Quality Control

Our p-Fluorotoluene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids and oxidizers. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 1.0%
Density (at 20°C)	1.000 - 1.005 g/mL
Refractive Index (n20D)	1.468 - 1.472

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.