Description

Benzenesulfonyl Fluoride, 4-Chloro- (9Ci) is a versatile organosulfur compound characterized by a reactive sulfonyl fluoride group and a chloro substituent. This combination makes it a valuable synthetic intermediate and chemical probe in advanced research and development. It is primarily utilized by professionals in the pharmaceutical and agrochemical industries for constructing complex molecules and studying biological systems.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly sulfonamide-based drugs.
• Chemical Biology Probe: Used in activity-based protein profiling (ABPP) to label and study serine hydrolase enzymes due to its reactive sulfonyl fluoride moiety.
• Agrochemical Synthesis: Intermediate in the production of herbicides, fungicides, and other crop protection agents.
• Material Science: Monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Organic Synthesis: Versatile reagent for introducing the 4-chlorobenzenesulfonyl group into target molecules.
• Bioconjugation: Employed for the selective and stable modification of proteins and peptides.

Basic Information

Product Name	Benzenesulfonyl Fluoride, 4-Chloro- (9Ci)
CAS No.	349-89-3
Molecular Formula	C6H4ClFO2S
Molecular Weight	194.61 g/mol
Synonyms	4-Chlorobenzenesulfonyl Fluoride; p-Chlorobenzenesulfonyl Fluoride; 1-Chloro-4-(fluorosulfonyl)benzene; Benzenesulfonyl fluoride, 4-chloro-; 4-Chlorophenylsulfonyl fluoride; NSC 404087; 4-Cl-Ph-SO2F
EINECS	Contact for details

Quality Control

Our Benzenesulfonyl Fluoride, 4-Chloro- (9Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	34 - 38 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.