Description

(Chlorodifluoromethyl)Benzene is a versatile fluorinated aromatic building block characterized by a reactive chlorodifluoromethyl group attached to a benzene ring. This compound is valued for its ability to introduce the difluoromethyl moiety into target molecules, a key modification in modern pharmaceutical and agrochemical design. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the metabolically stable difluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where fluorination enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with tailored properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and cross-coupling reactions to construct complex fluorinated organic molecules.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new fluorination methodologies and creating compound libraries.

Basic Information

Product Name	(Chlorodifluoromethyl)Benzene
CAS No.	349-50-8
Molecular Formula	C7H5ClF2
Molecular Weight	162.56 g/mol
Synonyms	α,α-Difluoro-α-chlorotoluene; Benzyl Chloride, α,α-Difluoro-; (Chlorodifluoromethyl)benzene; Benzyl Chloride, α,α-Difluoro-; Difluorochloromethylbenzene; 1-(Chlorodifluoromethyl)benzene; Phenyl(chlorodifluoro)methane; Benzotrifluoride, α-chloro-
EINECS	206-493-6

Quality Control

Our (Chlorodifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.