Description

4-Bromo-3-Nitrobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique trifluoromethyl and nitro-substituted bromobenzene structure makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic core with electron-withdrawing groups.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings, enabling the formation of new carbon-carbon bonds.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Bromo-3-Nitrobenzotrifluoride
CAS No.	349-03-1
Molecular Formula	C7H3BrF3NO2
Molecular Weight	270.00 g/mol
Synonyms	1-Bromo-4-(trifluoromethyl)-2-nitrobenzene; 2-Nitro-4-bromobenzotrifluoride; 4-Bromo-3-nitro-α,α,α-trifluorotoluene; 3-Nitro-4-bromobenzotrifluoride; Benzene, 1-bromo-4-(trifluoromethyl)-2-nitro-; α,α,α-Trifluoro-4-bromo-3-nitrotoluene; 4-Bromo-α,α,α-trifluoro-3-nitrotoluene; 4-Bromo-3-nitrobenzylidynetrifluoride
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.