Description

2-Chlorofluorobenzene is a versatile halogenated aromatic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chlorine and fluorine substituents, makes it a valuable intermediate for introducing specific reactivity and properties into target molecules. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic rings to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern contributes to efficacy and environmental profile.
• Liquid Crystal & Electronic Chemicals: Serves as a building block for fluorinated liquid crystal molecules and other electronic materials used in displays and semiconductors.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a starting material for generating more complex fluorinated arenes and ligands.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized fluorinated dyes and pigments with enhanced lightfastness and color properties.

Basic Information

Product Name	2-Chlorofluorobenzene
CAS No.	348-51-6
Molecular Formula	C6H4ClF
Molecular Weight	130.55 g/mol
Synonyms	1-Chloro-2-fluorobenzene; o-Chlorofluorobenzene; 2-Fluorochlorobenzene; ortho-Chlorofluorobenzene; Fluorochlorobenzene; Benzene, 1-chloro-2-fluoro-; 2-Chloro-1-fluorobenzene; o-Fluorochlorobenzene
EINECS	206-487-8

Quality Control

Our 2-Chlorofluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 1.0%
Density (20°C)	~1.25 g/mL
Boiling Point	~137°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.