Description

2-Bromo-5-Chlorobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its trifluoromethyl and halogen substituents make it a key intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the agrochemical and pharmaceutical industries, particularly for developing novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new drug candidates, especially those requiring halogenated aromatic cores for target binding.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating fluorinated components used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and altered refractive indices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	2-Bromo-5-Chlorobenzotrifluoride
CAS No.	344-65-0
Molecular Formula	C7H3BrClF3
Molecular Weight	259.45 g/mol
Synonyms	1-Bromo-4-chloro-2-(trifluoromethyl)benzene; 5-Chloro-2-bromobenzotrifluoride; 2-Bromo-5-chloro-α,α,α-trifluorotoluene; 2-Bromo-5-chloro-(trifluoromethyl)benzene; α,α,α-Trifluoro-2-bromo-5-chlorotoluene; Benzene, 1-bromo-4-chloro-2-(trifluoromethyl)-; (2-Bromo-5-chlorophenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chlorobenzotrifluoride is produced under a stringent quality management system to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and purity, and is accompanied by a comprehensive Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.75 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.