Description

6-Bromo-1-Fluoro-2,4-Dimethylbenzene is a high-purity halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. It is primarily used by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a halogenated, multi-substituted benzene core for bioactivity or further derivatization.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where the bromine and fluorine atoms serve as handles for introducing specific functional groups.
• Material Science Research: Serves as a monomer or building block for developing specialty polymers, liquid crystals, and organic electronic materials due to its aromatic stability and halogen reactivity.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, leveraging the bromine atom for carbon-carbon or carbon-heteroatom bond formation.
• Chemical Library Development: Employed in medicinal and combinatorial chemistry for generating diverse compound libraries for high-throughput screening.
• Fluorine Chemistry Studies: Used as a model compound in research exploring the effects of fluorine substitution on the physical and chemical properties of aromatic systems.

Basic Information

Product Name	6-Bromo-1-Fluoro-2,4-Dimethylbenzene
CAS No.	344-16-1
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	2-Bromo-5-fluoro-1,3-dimethylbenzene; 1-Bromo-2-fluoro-3,5-dimethylbenzene; 5-Fluoro-2,4-dimethylbromobenzene; 3,5-Dimethyl-4-fluorobromobenzene; 2,4-Dimethyl-5-fluorobromobenzene; 6-Bromo-1-fluoro-2,4-dimethylbenzol; 344-16-1; 6-Bromo-1-fluoro-2,4-dimethyl-benzene
EINECS	Contact for details

Quality Control

Our 6-Bromo-1-Fluoro-2,4-Dimethylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.