Description

2-Acetamide-5-Fluorotoluene is a specialized fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its core value lies in providing a versatile acetamide-toluene scaffold with a strategically placed fluorine atom, enabling precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for advanced polymers and liquid crystals, where fluorinated aromatic units impart unique thermal and chemical resistance.
• Organic Synthesis Reagent: Acts as a versatile intermediate for further functionalization, including hydrolysis to amines, halogenation, or coupling reactions in complex molecule assembly.

Basic Information

Product Name	2-Acetamide-5-Fluorotoluene
CAS No.	326-65-8
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	N-(5-Fluoro-2-methylphenyl)acetamide; 5'-Fluoro-2'-methylacetanilide; 2-Methyl-5-fluoroacetanilide; 1-Acetamido-5-fluoro-2-methylbenzene; 2-Acetamido-5-fluorotoluene; 5-Fluoro-2-methylacetanilide; Acetamide, N-(5-fluoro-2-methylphenyl)-; 2-Acetylamino-5-fluorotoluene
EINECS	206-312-8

Quality Control

Our 2-Acetamide-5-Fluorotoluene is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.