Description

2-Methyl-7-(Trifluoromethyl)Quinoline is a high-purity, fluorinated quinoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique combination of the quinoline scaffold and the trifluoromethyl group, which imparts desirable properties like enhanced lipophilicity and metabolic stability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to build novel active ingredients. Its reliable synthesis and consistent quality are paramount for scaling up discovery projects to commercial production.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Precursor: Employed in the research of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport layers, due to its electron-deficient quinoline structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized nitrogen-containing ligands used in transition metal catalysis for asymmetric synthesis.
• Fluorine Chemistry Research: An important substrate for studying the introduction and reactivity of fluorine-containing motifs in heterocyclic systems.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	2-Methyl-7-(Trifluoromethyl)Quinoline
CAS No.	324-32-3
Molecular Formula	C11H8F3N
Molecular Weight	211.18 g/mol
Synonyms	7-(Trifluoromethyl)-2-methylquinoline; 2-Methyl-7-trifluoromethylquinoline; Quinoline, 2-methyl-7-(trifluoromethyl)-; 7-Trifluoromethyl-2-methylquinoline; 2-Methyl-α,α,α-trifluoro-7-quinolinemethane
EINECS	Contact for details

Quality Control

Our 2-Methyl-7-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP (current Good Manufacturing Practice) guidelines where applicable, ensuring traceability and reliability for our global B2B clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.