Description

Benzene, 1-(Methylthio)-2-(Trifluoromethyl)- is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a methylthio and a trifluoromethyl group, makes it a valuable precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: A versatile reagent for introducing the SCF3 moiety or for further functionalization via the methylthio group in complex molecule construction.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development and exploring new chemical spaces in fluoroorganic chemistry.

Basic Information

Product Name	Benzene, 1-(Methylthio)-2-(Trifluoromethyl)-
CAS No.	322-58-7
Molecular Formula	C8H7F3S
Molecular Weight	192.20 g/mol
Synonyms	1-(Methylthio)-2-(trifluoromethyl)benzene; 2-(Trifluoromethyl)phenyl methyl sulfide; α,α,α-Trifluoro-o-(methylthio)toluene; o-(Methylthio)benzotrifluoride; 2-(Methylthio)benzotrifluoride; (2-Trifluoromethylphenyl) methyl sulfide; Methyl 2-trifluoromethylphenyl sulfide
EINECS	206-294-7

Quality Control

Our Benzene, 1-(Methylthio)-2-(Trifluoromethyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable sourcing in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, organic solvents, fluorides, and strong alkalis. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to minimize moisture uptake and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (g/mL at 20°C)	1.28 - 1.32

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.