Description

Carbonyl Cyanide Phenylhydrazone is a potent and specific mitochondrial uncoupler widely used in biochemical and pharmacological research. Its primary value lies in its ability to dissipate the proton gradient across the inner mitochondrial membrane, making it an essential tool for studying cellular respiration, ATP production, and metabolic pathways. This compound is critical for researchers and manufacturers in the fields of life sciences, pharmaceutical development, and metabolic disease research who require high-purity biochemical reagents.

Application

• Mitochondrial Research: A key tool for studying oxidative phosphorylation, proton leak, and mitochondrial bioenergetics.
• Metabolic Pathway Analysis: Used to investigate cellular metabolism, ATP synthesis, and the role of mitochondria in various disease states.
• Pharmacology & Toxicology: Employed in screening compounds for mitochondrial toxicity and understanding drug-induced metabolic dysfunction.
• Cell Biology Studies: Applied in research on apoptosis (programmed cell death), calcium signaling, and reactive oxygen species (ROS) generation.
• Biochemical Reagent: Serves as a critical component in assay kits and research protocols for academic and industrial laboratories.
• Reference Standard: Used as a high-purity analytical standard in quality control for related pharmaceutical compounds.

Basic Information

Product Name	Carbonyl Cyanide Phenylhydrazone
CAS No.	306-18-3
Molecular Formula	C9H5N3O
Molecular Weight	171.16 g/mol
Synonyms	CCCP; Carbonyl cyanide m-chlorophenyl hydrazone; 3-Chlorophenylhydrazonopropanedinitrile; m-Chlorocarbonylcyanide phenylhydrazone; 1-(3-Chlorophenyl)hydrazonopropanedinitrile; Uncoupler CCCP; Mitochondrial Uncoupler CCCP; [3-Chlorophenyl]hydrazonomalononitrile
EINECS	206-183-9

Quality Control

Our Carbonyl Cyanide Phenylhydrazone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.