Description

Proadifen is a versatile organic compound widely recognized for its role as a potent cytochrome P450 inhibitor and non-specific esterase inhibitor. This functionality makes it a critical tool in pharmacological and biochemical research for modulating drug metabolism and studying enzyme pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require high-purity biochemical reagents for advanced studies.

Application

• Pharmacological Research: Used extensively as a model cytochrome P450 inhibitor to study drug-drug interactions and metabolic pathways in vitro and in vivo.
• Biochemical Assays: Serves as a non-specific esterase inhibitor in enzymatic studies to prevent the hydrolysis of substrate esters.
• Drug Metabolism Studies: Employed to inhibit the metabolism of co-administered drugs, allowing researchers to investigate the role of specific enzymes.
• Toxicology Screening: Utilized in preclinical testing to assess the metabolic stability and potential toxicity of new chemical entities.
• Reference Standard: Acts as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: A key reagent for universities and research institutes conducting fundamental studies on enzyme kinetics and inhibition.

Basic Information

Product Name	Proadifen
CAS No.	302-33-0
Molecular Formula	C18H23NO
Molecular Weight	269.38 g/mol
Synonyms	SKF-525A; 2-(Diethylamino)ethyl 2,2-diphenylpentanoate; β-Diethylaminoethyldiphenylpropylacetate; Diphenylpropylacetic Acid β-Diethylaminoethyl Ester; Proadiphen; Precyclidine (related compound); Contact for details on additional trade names.
EINECS	206-123-1

Quality Control

Our Proadifen is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.