Description

Hexacosanoic Acid Methyl Ester-D3 is a deuterium-labeled internal standard of the long-chain fatty acid methyl ester, hexacosanoic acid methyl ester. This high-purity, isotopically labeled compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry-based analyses. It is primarily required by researchers and quality control laboratories in the pharmaceutical, biotechnology, and advanced materials sectors for precise metabolic studies, lipidomics, and method validation.

Application

• Quantitative Internal Standard in Mass Spectrometry (MS): Used for the accurate quantification of C26:0 fatty acids and their derivatives in complex biological matrices like plasma, tissues, and cell cultures.
• Lipidomics and Metabolomics Research: Serves as a critical reference standard in profiling and understanding lipid metabolism, signaling pathways, and disease biomarkers.
• Pharmaceutical Development and Bioanalysis: Employed in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug metabolism and ensure analytical method compliance with regulatory guidelines (e.g., FDA, EMA).
• Clinical Diagnostics: Facilitates the precise measurement of very long-chain fatty acids (VLCFAs), which is vital for diagnosing peroxisomal disorders such as adrenoleukodystrophy (ALD).
• Food and Nutritional Science: Used to analyze and quantify specific fatty acid esters in food products, supplements, and nutritional studies.
• Stable Isotope Labeling Studies: Acts as a tracer in metabolic flux analysis to investigate biosynthetic pathways and turnover rates.

Basic Information

Product Name	Hexacosanoic Acid Methyl Ester-D3
CAS No.	2743078-84-2
Molecular Formula	C₂₇H₅₁D₃O₂
Molecular Weight	413.72 g/mol (approx.)
Synonyms	Methyl Hexacosanoate-d3; Methyl Cerotate-d3; C26:0 Methyl Ester-d3; Deuterated Methyl Hexacosanoate; Methyl 26,26,26-trideuteriohexacosanoate; Cerotic Acid Methyl Ester-d3; n-Hexacosanoic Acid Methyl Ester-d3
EINECS	Contact for details

Quality Control

Every batch of Hexacosanoic Acid Methyl Ester-D3 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, GC-MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent residues is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, store at 2-8°C. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.