Description

4-Bromo-1-(2-Ethylhexyl)-2-Fluorobenzene is a high-purity, specialty fluorinated aromatic building block designed for advanced synthetic chemistry. This compound matters for its role as a key intermediate in the development of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine and bromine substituents is critical for modulating biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in life sciences, material science, and fine chemical industries seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Liquid Crystal & OLED Material Precursor: Acts as a starting material for synthesizing fluorinated aromatic cores used in advanced display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Material Science: Employed to create monomers and additives for specialty polymers, imparting desired properties like chemical resistance or altered refractive index.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi, Stille) to construct complex biaryl systems.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry groups exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	4-Bromo-1-(2-Ethylhexyl)-2-Fluorobenzene
CAS No.	2727165-39-9
Molecular Formula	C₁₄H₂₀BrF
Molecular Weight	287.21 g/mol
Synonyms	1-Bromo-4-(2-ethylhexyl)-2-fluorobenzene; 2-Fluoro-4-bromo-1-(2-ethylhexyl)benzene; 4-Bromo-2-fluoro-1-(2-ethylhexyl)benzene; 2-Ethylhexyl-4-bromo-2-fluorobenzene; (2-Ethylhexyl)-4-bromo-2-fluorobenzene; 4-Bromo-2-fluorophenyl(2-ethylhexyl) ether (common misnomer, check structure); Benzene, 1-bromo-4-(2-ethylhexyl)-2-fluoro-; CAS 2727165-39-9
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(2-Ethylhexyl)-2-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications such as assay (by HPLC or GC), identity confirmation (by IR and/or NMR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.