Description

3-Pyridinol, 6-Amino-4-Fluoro-, Hydrochloride (1:1) is a high-purity, fluorinated pyridine derivative salt, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both amino and fluoro substituents onto the pyridine core, enabling precise modifications in target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of new drug candidates, particularly in areas requiring fluorinated heterocycles for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential building block for creating specialized ligands, catalysts, or functionalized polymers with specific electronic properties.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in related chemical processes.

Basic Information

Product Name	3-Pyridinol, 6-Amino-4-Fluoro-, Hydrochloride (1:1)
CAS No.	2703752-58-1
Molecular Formula	C5H6FN2O·HCl
Molecular Weight	164.57 g/mol (Free base) / 201.03 g/mol (HCl salt)
Synonyms	6-Amino-4-fluoro-3-pyridinol hydrochloride; 4-Fluoro-6-amino-3-pyridinol hydrochloride; 3-Hydroxy-6-amino-4-fluoropyridine hydrochloride; 6-Amino-4-fluoropyridin-3-ol hydrochloride; AFPH; Aminofluoropyridinol HCl
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinol, 6-Amino-4-Fluoro-, Hydrochloride (1:1) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.