Description

2-Propen-1-One, 1-[4-[8-[[3-Methyl-4-[(1-Methyl-1H-Benzimidazol-5-Yl)Oxy]Phenyl]Amino]Pyrimido[5,4-D]Pyrimidin-2-Yl]-1-Piperazinyl]- is a sophisticated, high-value organic compound featuring a complex molecular architecture designed for targeted applications. This compound matters as a key advanced intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics, particularly in oncology and other specialized disease areas. Pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in cutting-edge drug discovery and synthesis require this high-purity building block for their critical research and development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel, targeted small-molecule drugs.
• Oncology Research: Used in the development and study of potential kinase inhibitors and other anti-cancer agents due to its pyrimidopyrimidine and benzimidazole motifs.
• Biochemical Research: Acts as a reference standard or a probe molecule in biochemical assays to study specific enzyme interactions and signaling pathways.
• Preclinical Development: Employed in the production of batches for pharmacological, pharmacokinetic, and toxicological studies during drug candidate evaluation.
• Process Chemistry: Utilized by process chemists to develop and optimize scalable, cost-effective synthetic routes for advanced pharmaceutical compounds.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) providing bespoke chemical synthesis services.

Basic Information

Item	Detail
Product Name	2-Propen-1-One, 1-[4-[8-[[3-Methyl-4-[(1-Methyl-1H-Benzimidazol-5-Yl)Oxy]Phenyl]Amino]Pyrimido[5,4-D]Pyrimidin-2-Yl]-1-Piperazinyl]-
CAS No.	2682003-36-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-[4-[8-[[3-Methyl-4-[(1-Methyl-1H-Benzimidazol-5-Yl)Oxy]Phenyl]Amino]Pyrimido[5,4-d]Pyrimidin-2-Yl]-1-Piperazinyl]-2-Propen-1-One; Advanced Kinase Inhibitor Intermediate; Pyrimido[5,4-d]pyrimidine derivative; Benzimidazole ether acrylamide; Targeted Therapy Intermediate; CAS 2682003-36-5
EINECS	Contact for details

Quality Control

Our 2-Propen-1-One, 1-[4-[8-[[3-Methyl-4-[(1-Methyl-1H-Benzimidazol-5-Yl)Oxy]Phenyl]Amino]Pyrimido[5,4-D]Pyrimidin-2-Yl]-1-Piperazinyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.