Description

Sirt6 Activator 12Q is a high-purity, small-molecule compound designed for targeted biological research. This product is a potent and selective activator of the Sirtuin 6 (SIRT6) enzyme, a key regulator of cellular metabolism, stress response, and genomic stability. It is an essential research tool for academic institutions, pharmaceutical R&D departments, and biotechnology companies investigating aging, metabolic disorders, and oncology. The compound is supplied with full analytical documentation to ensure reproducibility and reliability in critical experiments.

Application

• Biochemical Research: Used as a specific probe to study SIRT6 enzyme kinetics, deacetylation activity, and downstream signaling pathways in vitro.
• Cell-Based Assays: Applied in cellular models to investigate the role of SIRT6 activation in glucose homeostasis, lipid metabolism, and inflammatory responses.
• Drug Discovery & Preclinical Studies: Serves as a reference compound or lead molecule in screening campaigns and proof-of-concept studies for age-related and metabolic diseases.
• Academic Research: Facilitates fundamental research in epigenetics, DNA repair mechanisms, and the biology of aging.
• Biomarker Studies: Helps elucidate the connection between SIRT6 function and potential diagnostic or prognostic biomarkers.

Basic Information

Product Name	Sirt6 Activator 12Q
CAS No.	2601734-99-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	12Q; SIRT6 Activator 12Q; Sirtuin 6 Activator 12Q; CAS 2601734-99-8; 1,2,4-Thiadiazole-3-carboxamide derivative (SIRT6 activator); Research compound 12Q
EINECS	Contact for details

Quality Control

Our Sirt6 Activator 12Q is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, which is critical for reliable research outcomes. Each lot undergoes comprehensive analytical characterization, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the exact specifications and test results. We support research compliance with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.