Description

1,3-Dibromo-2-Butoxy-5-Fluorobenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique substitution pattern enables precise structural modifications. Industrial researchers and process chemists need it for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Material Science: Employed in the production of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and halogen functionalities.
• Chemical Research & Development: Acts as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Catalyst & Ligand Preparation: Useful for synthesizing sophisticated, fluorinated ligands used in cross-coupling and other transition metal-catalyzed reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and scale-up projects.

Basic Information

Product Name	1,3-Dibromo-2-Butoxy-5-Fluorobenzene
CAS No.	2484888-99-3
Molecular Formula	C10H11Br2FO
Molecular Weight	334.00 g/mol
Synonyms	2-Butoxy-1,3-dibromo-5-fluorobenzene; 5-Fluoro-1,3-dibromo-2-butoxybenzene; 1,3-Dibromo-5-fluoro-2-butoxybenzene; Benzene, 1,3-dibromo-2-butoxy-5-fluoro-; 2484888-99-3; DBFB (abbreviation)
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-2-Butoxy-5-Fluorobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed and stored in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.