Description

Il-17A Inhibitor 1 CAS NO 2452464-73-0 is a potent and selective small molecule inhibitor targeting the Interleukin-17A (IL-17A) cytokine pathway. This compound is of significant interest for its role in modulating inflammatory and autoimmune responses, offering a targeted approach for therapeutic research and development. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions engaged in immunology, inflammation biology, and novel drug discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) in the preclinical development of novel anti-inflammatory and autoimmune disease therapeutics.
• Immunology & Inflammation Studies: Used as a precise biochemical tool to investigate the IL-17 signaling pathway, cytokine biology, and mechanisms of immune-mediated diseases in vitro and in vivo.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) assays and structure-activity relationship (SAR) studies to identify and optimize next-generation IL-17 pathway inhibitors.
• Biomarker & Mechanism of Action Research: Facilitates studies on disease biomarkers and the elucidation of therapeutic mechanisms for conditions like psoriasis, psoriatic arthritis, and ankylosing spondylitis.
• Academic & Contract Research: Essential for basic scientific research in university laboratories and for specialized testing services offered by contract research organizations (CROs).

Basic Information

Product Name	Il-17A Inhibitor 1
CAS No.	2452464-73-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	IL-17A Inhibitor 1; IL17A Inhibitor 1; Interleukin-17A Inhibitor 1; 2452464-73-0; (S)-2-(4-(2-Hydroxypropan-2-yl)phenyl)-N-(2-methyl-4-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl)propanamide; BMS-986251; BMS986251
EINECS	Contact for details

Quality Control

Our Il-17A Inhibitor 1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. The material is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.