Description

Egfr-In-8 is a potent and selective small-molecule inhibitor targeting the Epidermal Growth Factor Receptor (EGFR), a key protein in cellular signaling pathways. This high-purity compound is essential for biochemical research, enabling the study of oncogenic signaling and the development of targeted cancer therapies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, drug discovery, and molecular biology.

Application

• Biochemical Research: Used as a selective tool compound to study EGFR-mediated signaling cascades and their role in cell proliferation and survival.
• Oncology Drug Discovery: Serves as a reference standard and lead compound in the development of novel targeted cancer therapeutics.
• Cellular Assay Development: Employed to validate and optimize high-throughput screening assays for identifying new EGFR inhibitors.
• Mechanistic Studies: Facilitates research into drug resistance mechanisms and combination therapy strategies in EGFR-driven cancers.
• Academic Research: A critical reagent for university and institutional labs investigating tyrosine kinase biology and pathology.

Basic Information

Product Name	Egfr-In-8
CAS No.	2407957-87-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	EGFR-IN-8; EGFR Inhibitor-8; 2407957-87-1; Epidermal Growth Factor Receptor Inhibitor 8; Egfr Inhibitor 8; EGFR Tyrosine Kinase Inhibitor-8; EGFR-TKI-8
EINECS	Contact for details

Quality Control

Our Egfr-In-8 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to support your research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.