Description

Akt-In-3 is a potent and selective small molecule inhibitor of the Akt (Protein Kinase B) signaling pathway, a critical regulator of cell growth, proliferation, and survival. This compound is essential for researchers and developers targeting oncology, metabolic disorders, and other diseases driven by aberrant PI3K/Akt/mTOR signaling. It is primarily utilized in pharmaceutical R&D for target validation, mechanism-of-action studies, and as a key intermediate in the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: A critical tool compound for studying the role of Akt kinases in cancer biology, cellular signaling pathways, and apoptosis.
• Preclinical Drug Discovery: Used as a reference standard and a pharmacologically active scaffold in the design and optimization of new oncology therapeutics.
• Biochemical Assays: Employed in high-throughput screening (HTS) and in vitro kinase assays to evaluate the potency and selectivity of novel Akt inhibitors.
• Cell-Based Studies: Facilitates the investigation of downstream effects of Akt inhibition on cell proliferation, metabolism, and survival in various cancer cell lines.
• Academic Research: Supports fundamental biological research in universities and institutes focused on signal transduction and molecular oncology.

Basic Information

Product Name	Akt-In-3
CAS No.	2374740-21-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Akt Inhibitor 3; Akti-3; Akt-IN-3; 2374740-21-1; Akt pathway inhibitor 3; Protein Kinase B Inhibitor III
EINECS	Contact for details

Quality Control

Our Akt-In-3 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and identity confirmation. A detailed Certificate of Analysis (COA) documenting purity, assay, and related substances is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.