Description

Cdk9-In-7 CAS NO 2369981-71-3 is a potent and selective small molecule inhibitor of Cyclin-Dependent Kinase 9 (CDK9), a key regulator of transcription. This compound is a critical research tool for investigating transcriptional control, cell cycle progression, and apoptosis in various disease models. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on oncology, virology, and other therapeutic areas where CDK9 inhibition is of high interest.

Application

• Biochemical Research: Used as a selective inhibitor to study CDK9 kinase activity and its role in transcriptional elongation in vitro.
• Cell-Based Assays: Applied in cellular models to investigate the effects of CDK9 inhibition on gene expression, cell cycle arrest, and programmed cell death.
• Oncology Research: A valuable probe for exploring CDK9 as a therapeutic target in cancers driven by transcriptional dependencies, such as certain leukemias and solid tumors.
• Virology Studies: Employed in research to understand the role of host CDK9 in viral replication, particularly for viruses like HIV that require this kinase.
• Drug Discovery & Development: Serves as a reference compound or a starting point for the design and screening of novel CDK9-targeted therapeutics.
• Signal Transduction Pathway Analysis: Helps elucidate the broader P-TEFb complex signaling network and its implications in disease.

Basic Information

Product Name	Cdk9-In-7
CAS No.	2369981-71-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CDK9-IN-7; Cdk9 Inhibitor 7; 2369981-71-3; Cyclin-Dependent Kinase 9 Inhibitor 7; CDK9i-7
EINECS	Contact for details

Quality Control

Our Cdk9-In-7 is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.