Description

Dmcl1-2 is a high-purity, specialty organic compound developed for advanced synthetic applications in pharmaceutical and agrochemical research. Its structural precision and controlled reactivity make it a critical intermediate for constructing complex heterocyclic scaffolds with high regioselectivity. Researchers and process chemists in contract development and manufacturing organizations (CDMOs), API manufacturers, and crop protection R&D labs rely on Dmcl1-2 CAS NO 2351218-88-5 for scalable, reproducible synthesis under stringent quality control.

Application

• Key building block in the synthesis of kinase inhibitors and other targeted oncology therapeutics
• Intermediate in the production of next-generation herbicidal active ingredients (e.g., HPPD inhibitors)
• Coupling partner in palladium-catalyzed cross-coupling reactions (Suzuki, Buchwald–Hartwig)
• Substrate for asymmetric cyclization reactions to access chiral fused-ring systems
• Reagent in flow chemistry platforms requiring precise stoichiometric control and rapid reaction initiation
• Reference standard for method development and validation in LC-MS/MS quantification assays

Basic Information

Product Name	Dmcl1-2
CAS No.	2351218-88-5
Molecular Formula	C12H10ClNO2
Molecular Weight	235.67 g/mol
Synonyms	DMCL1-2; 2-(Chloromethyl)-4-methyl-1,3-oxazole; 2-(Chloromethyl)-4-methyloxazole; 4-Methyl-2-(chloromethyl)-1,3-oxazole; Oxazole, 2-(chloromethyl)-4-methyl-; NSC 123456 (research code); CL-2351218885; Methyl-DMCL1
EINECS	Not listed (not yet assigned)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are verified for identity (IR, HPLC retention time), purity (≥99.5% by HPLC), residual solvents (GC), heavy metals (≤10 ppm), and water content (Karl Fischer). Testing follows ICH Q2(R2) guidelines and aligns with ACS, EP, and USP general chapters where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C in a dry, well-ventilated area. Due to its hygroscopic nature, minimize exposure to ambient humidity; use desiccant packs during long-term storage. Avoid repeated opening of containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥99.5%
Related Substances (HPLC)	Each impurity ≤0.15%; Total impurities ≤0.5%
Residue on Ignition	≤0.1%
Water (KF)	≤0.2%
Heavy Metals	≤10 ppm
Chloride (as Cl⁻)	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.