Description

Ahr Antagonist 2 is a potent and selective small-molecule inhibitor of the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor involved in numerous biological pathways. This compound is crucial for researchers and developers targeting inflammatory diseases, autoimmune disorders, and oncology, where dysregulated AhR signaling is implicated. It serves as a valuable tool for biochemical research, high-throughput screening, and preclinical development within the pharmaceutical and biotechnology sectors.

Application

• Biochemical Research: Used as a selective probe to study AhR signaling pathways, receptor-ligand interactions, and downstream gene expression effects in vitro.
• Drug Discovery: Serves as a reference compound or lead structure in high-throughput screening campaigns for developing novel anti-inflammatory or immunomodulatory therapeutics.
• Inflammatory Disease Models: Applied in preclinical research to investigate the role of AhR in conditions like psoriasis, rheumatoid arthritis, and inflammatory bowel disease (IBD).
• Oncology Research: Utilized to explore the complex role of AhR in tumor immunology, cancer cell proliferation, and the tumor microenvironment.
• Toxicology Studies: Employed to antagonize AhR activation by environmental toxins (e.g., dioxins), helping to elucidate mechanisms of toxicity and identify potential protective agents.

Basic Information

Product Name	Ahr Antagonist 2
CAS No.	2338747-54-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	AhR Antagonist 2; AHR Antagonist II; Aryl Hydrocarbon Receptor Antagonist 2; CAS 2338747-54-7; [IUPAC/Systematic Name - Contact for details]; [Common Research Code - Contact for details]
EINECS	Contact for details

Quality Control

Our Ahr Antagonist 2 is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Identity and purity are confirmed using advanced analytical techniques including HPLC and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, analytical methods, and results is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under desiccated conditions. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.