Description

Fgfr1/Ddr2 Inhibitor 1 CAS NO 2308497-58-5 is a potent and selective small molecule inhibitor targeting the Fibroblast Growth Factor Receptor 1 (FGFR1) and Discoidin Domain Receptor 2 (DDR2) kinases. This compound is a critical research tool for investigating signaling pathways involved in cell proliferation, differentiation, and migration, with significant implications in oncology and fibrosis research. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies for target validation, mechanism-of-action studies, and preclinical drug discovery programs.

Application

• Biomedical Research: A key reagent for studying the role of FGFR1 and DDR2 in cancer biology, cellular signaling, and disease mechanisms.
• Drug Discovery & Development: Used in high-throughput screening (HTS), hit-to-lead optimization, and as a pharmacological probe in preclinical models.
• Oncology Research: Investigating potential therapeutic applications for cancers driven by FGFR1 or DDR2 dysregulation, such as certain lung, breast, and gastric cancers.
• Fibrosis & Tissue Remodeling Studies: Exploring the compound's effects on pathways involved in pulmonary fibrosis, liver fibrosis, and other fibrotic diseases.
• Cell Biology & Biochemistry: Tool compound for kinase selectivity profiling, understanding downstream signaling cascades (e.g., MAPK, PI3K/AKT), and cellular phenotype assays.
• Chemical Biology: Serves as a scaffold for the design and synthesis of novel analogs with improved potency or selectivity profiles.

Basic Information

Product Name	Fgfr1/Ddr2 Inhibitor 1
CAS No.	2308497-58-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	FGFR1/DDR2 Inhibitor 1; FGFR1/DDR2-IN-1; DDR2/FGFR1 Inhibitor; 2308497-58-5; FGFR1 and DDR2 dual inhibitor; Compound 2308497-58-5; Research compound 2308497-58-5; Kinase inhibitor 2308497-58-5
EINECS	Contact for details

Quality Control

Our Fgfr1/Ddr2 Inhibitor 1 is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and structural confirmation by NMR and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and potency are provided with every shipment to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term storage (up to 4 weeks), the product may be kept at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. Store under inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity (IC50)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.