Description

Flt3-In-4 CAS NO 2304799-09-3 is a potent and selective small molecule inhibitor of the FMS-like tyrosine kinase 3 (FLT3) receptor, a key target in hematological malignancies. This compound is crucial for advancing research into targeted cancer therapies, particularly for acute myeloid leukemia (AML). It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology drug discovery and preclinical studies.

Application

• Oncology Research & Drug Discovery: As a selective FLT3 inhibitor for investigating signaling pathways and validating FLT3 as a therapeutic target.
• Biochemical Assay Development: Used as a reference standard or active control in high-throughput screening (HTS) and enzymatic assays.
• Preclinical Studies: For evaluating efficacy, pharmacokinetics, and pharmacodynamics in cellular and animal models of FLT3-driven cancers.
• Mechanism of Action (MoA) Studies: To study apoptosis, cell proliferation, and differentiation in leukemia cell lines.
• Combination Therapy Research: For exploring synergistic effects with other chemotherapeutic agents or targeted therapies.
• Chemical Probe: A valuable tool compound for understanding the role of FLT3 in normal and pathological hematopoiesis.

Basic Information

Product Name	Flt3-In-4
CAS No.	2304799-09-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Flt3-In-4; FLT3 Inhibitor 4; 2304799-09-3; FMS-like tyrosine kinase 3 inhibitor 4; FLT3-IN-4; FLT3 tyrosine kinase inhibitor 4
EINECS	Contact for details

Quality Control

Our Flt3-In-4 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.