Description

Fluorinated Vhl Spy Molecule 4 is a specialized synthetic organic compound designed for advanced research and development applications. This high-value molecule is engineered to serve as a critical tool in chemical biology and pharmaceutical discovery, offering unique properties derived from its fluorinated structure. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical R&D departments engaged in probe development, target validation, and mechanism-of-action studies.

Application

• Chemical Biology Probe: Used as a high-affinity, selective probe for studying protein-protein interactions and target engagement in cellular systems.
• Pharmaceutical Research: Serves as a key intermediate or reference standard in the discovery and development of novel therapeutic agents, particularly in oncology and immunology.
• Proteolysis-Targeting Chimera (PROTAC) Development: Functions as a warhead or linker component in the design of targeted protein degradation platforms.
• Diagnostic Agent Development: Employed in the research and synthesis of advanced imaging agents for positron emission tomography (PET) or other molecular imaging techniques.
• Bioconjugation: Acts as a reactive handle for site-specific labeling of biomolecules such as antibodies, peptides, or oligonucleotides.
• Mechanistic Studies: Utilized to investigate enzymatic pathways, signal transduction, and other complex biological processes at the molecular level.

Basic Information

Product Name	Fluorinated Vhl Spy Molecule 4
CAS No.	2290526-31-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	VHL Ligand 4; Fluorinated VHL Ligand; VHL Spy Molecule 4; E3 Ligase Ligand; VHL-Targeting Molecule; Fluorinated Probe 2290526-31-5; (S,R,S)-AHPC-Me Fluorinated Analog; PROTAC Linker Component
EINECS	Contact for details

Quality Control

Our Fluorinated Vhl Spy Molecule 4 is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the product label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.