Description

Chmfl-Abl-121 is a high-purity, small molecule chemical compound identified by CAS number 2270879-07-5. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) in advanced research and development, particularly in the field of targeted therapeutics. It is essential for pharmaceutical companies, biotechnology research institutions, and academic laboratories engaged in the synthesis of novel drug candidates and biochemical studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel tyrosine kinase inhibitors and other targeted cancer therapies.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and signal transduction pathway studies.
• Preclinical Development: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology studies in drug discovery pipelines.
• Academic Research: Utilized in university and institutional labs for investigating protein-ligand interactions and structure-activity relationships (SAR).
• Process Chemistry: Acts as a starting material or intermediate for scale-up and optimization of synthetic routes under GMP or non-GMP conditions.

Basic Information

Product Name	Chmfl-Abl-121
CAS No.	2270879-07-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Chmfl-Abl-121; 2270879-07-5; ABL-121; Chmfl Abl 121; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile (Tentative IUPAC based on naming pattern); TKI Inhibitor ABL-121; Kinase Inhibitor 121
EINECS	Contact for details

Quality Control

Our Chmfl-Abl-121 is manufactured and controlled under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.