Description

Md2-Tlr4-In-1 CAS NO 2249801-12-3 is a high-purity, small molecule inhibitor designed for advanced biochemical and pharmacological research. This compound is critical for scientists investigating the intricate signaling pathways of innate immunity and inflammation. It is primarily utilized by research institutions and pharmaceutical R&D departments focused on immunology, oncology, and neuroinflammation studies.

Application

• Biochemical Research: Used as a selective inhibitor in studies targeting Toll-like receptor 4 (TLR4) and myeloid differentiation factor 2 (MD2) complex interactions.
• Immunology Studies: Essential for elucidating mechanisms of inflammation, sepsis, and autoimmune disease pathways in in vitro and cellular assays.
• Drug Discovery: Serves as a key reference standard and pharmacophore in the development of novel anti-inflammatory and immunomodulatory therapeutics.
• Academic Research: Employed in university and institutional labs for fundamental research into pattern recognition receptors and host defense mechanisms.
• Biopharmaceutical Development: Used in assay development and high-throughput screening (HTS) campaigns to identify new drug candidates.

Basic Information

Product Name	Md2-Tlr4-In-1
CAS No.	2249801-12-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MD2-TLR4-IN-1; TLR4/MD2 Inhibitor; MD2-TLR4 antagonist; 2249801-12-3; TLR4 signaling inhibitor; Myeloid differentiation protein 2 inhibitor; Innate immunity inhibitor; Small molecule TLR4 antagonist
EINECS	Contact for details

Quality Control

Our Md2-Tlr4-In-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the exacting standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.