Description

Stearoyl-L-Carnitine-D3 (Chloride) is a high-purity, deuterium-labeled derivative of L-carnitine, specifically modified with a stearoyl group. This compound serves as a critical internal standard and reference material in quantitative bioanalytical research, ensuring precise and accurate measurement of carnitine and acylcarnitine species. It is primarily utilized by pharmaceutical R&D laboratories, clinical diagnostics developers, and academic researchers focused on metabolic studies, lipidomics, and drug metabolism and pharmacokinetics (DMPK) analysis.

Application

• Quantitative Mass Spectrometry (MS) Analysis: Essential as a deuterated internal standard for the precise quantification of endogenous stearoylcarnitine and related metabolites in biological samples via LC-MS/MS.
• Clinical Diagnostics & Biomarker Research: Used in the development and validation of assays for metabolic disorders, such as inborn errors of metabolism, where acylcarnitine profiles are diagnostic.
• Pharmaceutical R&D: Supports drug discovery and development studies in lipid metabolism, enabling accurate tracking of drug-induced changes in acylcarnitine levels.
• Metabolomics & Lipidomics: A key reference compound in high-throughput profiling studies to identify and quantify perturbations in metabolic pathways.
• Stable Isotope Labeling Studies: Employed in tracer experiments to investigate fatty acid oxidation and mitochondrial function dynamics.
• Quality Control & Method Validation: Serves as a certified reference material to ensure the accuracy, precision, and reproducibility of analytical methods in contract research organizations (CROs) and testing labs.

Basic Information

Product Name	Stearoyl-L-Carnitine-D3 (Chloride)
CAS No.	2245711-27-5
Molecular Formula	C₂₅H₄₇D₃ClNO₄
Molecular Weight	~467.12 g/mol (Contact for exact weight)
Synonyms	L-Stearoylcarnitine-d3 Chloride; (3R)-3-[(1-Oxooctadecyl-18,18,18-d3)oxy]-4-(trimethylammonio)butanoate Chloride; O-Stearoyl-L-carnitine-d3 chloride; Octadecanoyl-L-carnitine-d3 chloride; Deuterated Stearoylcarnitine Chloride; C18:0 Carnitine-d3 Chloride; Internal Standard for Acylcarnitine Analysis-d3
EINECS	Contact for details

Quality Control

Our Stearoyl-L-Carnitine-D3 (Chloride) is manufactured under strict quality systems to ensure the highest standards of purity and isotopic enrichment, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and identity confirmation. We adhere to relevant guidelines for reference standards, and specifications can be aligned with customer requirements for research use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (by NMR)	≥ 90%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.